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Development of Novel Paclitaxel-Loaded ZIF-8 Metal-Organic Framework Nanoparticles Modified with Peptide Dimers and an Evaluation of Its Inhibitory Effect against Prostate Cancer Cells

Prostate cancer (PC) is one of the common malignant tumors of the male genitourinary system. Here, we constructed PTX@ZIF-8, which is a metal-organic-framework-encapsulated drug delivery nanoparticle with paclitaxel (PTX) as a model drug, and further modified the synthesized peptide dimer (Di-PEG(20...

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Detalles Bibliográficos
Autores principales: Zhao, Heming, Gong, Liming, Wu, Hao, Liu, Chao, Liu, Yanhong, Xiao, Congcong, Liu, Chenfei, Chen, Liqing, Jin, Mingji, Gao, Zhonggao, Guan, Youyan, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383971/
https://www.ncbi.nlm.nih.gov/pubmed/37514059
http://dx.doi.org/10.3390/pharmaceutics15071874