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Neuroprotection in an Experimental Model of Multiple Sclerosis via Opening of Big Conductance, Calcium-Activated Potassium Channels

Big conductance calcium-activated (BK) channel openers can inhibit pathologically driven neural hyperactivity to control symptoms via hyperpolarizing signals to limit neural excitability. We hypothesized that BK channel openers would be neuroprotective during neuroinflammatory, autoimmune disease. T...

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Detalles Bibliográficos
Autores principales: Pryce, Gareth, Sisay, Sofia, Giovannoni, Gavin, Selwood, David L., Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383993/
https://www.ncbi.nlm.nih.gov/pubmed/37513884
http://dx.doi.org/10.3390/ph16070972