Development and Characterization of an In Vitro Cell-Based Assay to Predict Potency of mRNA–LNP-Based Vaccines

Messenger RNA (mRNA) vaccines have emerged as a flexible platform for vaccine development. The evolution of lipid nanoparticles as effective delivery vehicles for modified mRNA encoding vaccine antigens was demonstrated by the response to the COVID-19 pandemic. The ability to rapidly develop effecti...

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Detalles Bibliográficos
Autores principales: Patel, Nisarg, Davis, Zach, Hofmann, Carl, Vlasak, Josef, Loughney, John W., DePhillips, Pete, Mukherjee, Malini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383996/
https://www.ncbi.nlm.nih.gov/pubmed/37515040
http://dx.doi.org/10.3390/vaccines11071224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383996/
https://www.ncbi.nlm.nih.gov/pubmed/37515040
http://dx.doi.org/10.3390/vaccines11071224

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