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Development and Characterization of an In Vitro Cell-Based Assay to Predict Potency of mRNA–LNP-Based Vaccines
Messenger RNA (mRNA) vaccines have emerged as a flexible platform for vaccine development. The evolution of lipid nanoparticles as effective delivery vehicles for modified mRNA encoding vaccine antigens was demonstrated by the response to the COVID-19 pandemic. The ability to rapidly develop effecti...
Autores principales: | Patel, Nisarg, Davis, Zach, Hofmann, Carl, Vlasak, Josef, Loughney, John W., DePhillips, Pete, Mukherjee, Malini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383996/ https://www.ncbi.nlm.nih.gov/pubmed/37515040 http://dx.doi.org/10.3390/vaccines11071224 |
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