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Hydrogel Delivery Device for the In Vitro and In Vivo Sustained Release of Active rhGALNS Enzyme

Morquio A disease is a genetic disorder resulting in N-acetylgalactosamine-6-sulfate sulfatase (GALNS) deficiency, and patients are currently treated with enzyme replacement therapy via weekly intravenous enzyme infusions. A means of sustained enzyme delivery could improve patient quality of life by...

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Detalles Bibliográficos
Autores principales: Flanagan, Michael, Gan, Qi, Sheth, Saahil, Schafer, Rachel, Ruesing, Samuel, Winter, Linda E., Toth, Karoly, Zustiak, Silviya P., Montaño, Adriana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384033/
https://www.ncbi.nlm.nih.gov/pubmed/37513843
http://dx.doi.org/10.3390/ph16070931