Passive Transfer of Animal-Derived Polyclonal Hyperimmune Antibodies Provides Protection of Mice from Lethal Lassa Virus Infection

Background: Lassa virus (LASV) can cause severe acute systemic infection in humans. No approved antiviral drugs or vaccines are currently available. Antibody-based therapeutics are considered a promising treatment strategy in the management of LASV disease. Methods: We used chimeric Ifnar(−/−) C57BL...

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Detalles Bibliográficos
Autores principales: Oestereich, Lisa, Müller-Kräuter, Helena, Pallasch, Elisa, Strecker, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384048/
https://www.ncbi.nlm.nih.gov/pubmed/37515124
http://dx.doi.org/10.3390/v15071436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384048/
https://www.ncbi.nlm.nih.gov/pubmed/37515124
http://dx.doi.org/10.3390/v15071436

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