Mirogabalin Decreases Pain-like Behaviors by Inhibiting the Microglial/Macrophage Activation, p38MAPK Signaling, and Pronociceptive CCL2 and CCL5 Release in a Mouse Model of Neuropathic Pain

Neuropathic pain is a chronic condition that significantly reduces the quality of life of many patients as a result of ineffective pain relief therapy. For that reason, looking for new analgesics remains an important issue. Mirogabalin is a new gabapentinoid that is a specific ligand for the α2σ-1 a...

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Detalles Bibliográficos
Autores principales: Zajączkowska, Renata, Pawlik, Katarzyna, Ciapała, Katarzyna, Piotrowska, Anna, Ciechanowska, Agata, Rojewska, Ewelina, Kocot-Kępska, Magdalena, Makuch, Wioletta, Wordliczek, Jerzy, Mika, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384153/
https://www.ncbi.nlm.nih.gov/pubmed/37513935
http://dx.doi.org/10.3390/ph16071023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384153/
https://www.ncbi.nlm.nih.gov/pubmed/37513935
http://dx.doi.org/10.3390/ph16071023

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