Cargando…
Mirogabalin Decreases Pain-like Behaviors by Inhibiting the Microglial/Macrophage Activation, p38MAPK Signaling, and Pronociceptive CCL2 and CCL5 Release in a Mouse Model of Neuropathic Pain
Neuropathic pain is a chronic condition that significantly reduces the quality of life of many patients as a result of ineffective pain relief therapy. For that reason, looking for new analgesics remains an important issue. Mirogabalin is a new gabapentinoid that is a specific ligand for the α2σ-1 a...
Autores principales: | Zajączkowska, Renata, Pawlik, Katarzyna, Ciapała, Katarzyna, Piotrowska, Anna, Ciechanowska, Agata, Rojewska, Ewelina, Kocot-Kępska, Magdalena, Makuch, Wioletta, Wordliczek, Jerzy, Mika, Joanna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384153/ https://www.ncbi.nlm.nih.gov/pubmed/37513935 http://dx.doi.org/10.3390/ph16071023 |
Ejemplares similares
-
Mirogabalin Decreases Pain-like Behaviours and Improves Opioid and Ketamine Antinociception in a Mouse Model of Neuropathic Pain
por: Zajączkowska, Renata, et al.
Publicado: (2022) -
Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain
por: Zajaczkowska, Renata, et al.
Publicado: (2020) -
Blockade of CC Chemokine Receptor Type 3 Diminishes Pain and Enhances Opioid Analgesic Potency in a Model of Neuropathic Pain
por: Pawlik, Katarzyna, et al.
Publicado: (2021) -
Phenytoin Decreases Pain-like Behaviors and Improves Opioid Analgesia in a Rat Model of Neuropathic Pain
por: Kocot-Kępska, Magdalena, et al.
Publicado: (2023) -
Dataset of (±)-NBI-74330 (CXCR3 antagonist) influence on chemokines under neuropathic pain
por: Piotrowska, Anna, et al.
Publicado: (2018)