In Vitro and In Silico Evaluation of Antiproliferative Activity of New Isoxazolidine Derivatives Targeting EGFR: Design, Synthesis, Cell Cycle Analysis, and Apoptotic Inducers

A series of novel enantiopure isoxazolidine derivatives were synthesized and evaluated for their anticancer activities against three human cancer cell lines such as human breast carcinoma (MCF-7), human lung adenocarcinoma (A-549), and human ovarian carcinoma (SKOV3) by employing MTT assay. The synt...

Descripción completa

Detalles Bibliográficos
Autores principales: Alminderej, Fahad, Ghannay, Siwar, Omer Elsamani, Mohamed, Alhawday, Fahad, Albadri, Abuzar E. A. E., Elbehairi, Serag Eldin I., Alfaifi, Mohammad Y., Kadri, Adel, Aouadi, Kaïss
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384175/
https://www.ncbi.nlm.nih.gov/pubmed/37513936
http://dx.doi.org/10.3390/ph16071025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384175/
https://www.ncbi.nlm.nih.gov/pubmed/37513936
http://dx.doi.org/10.3390/ph16071025

Ejemplares similares