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SGLT1/2 inhibition improves glycemic control and multi-organ protection in type 1 diabetes

Sodium glucose cotransporters (SGLTs) are transport proteins that are expressed throughout the body. Inhibition of SGLTs is a relatively novel therapeutic strategy to improve glycemic control and has been shown to promote cardiorenal benefits. Dual SGLT1/2 inhibitors (SGLT1/2i) such as sotagliflozin...

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Detalles Bibliográficos
Autores principales: Herat, Lakshini Yasaswi, Matthews, Jennifer Rose, Hibbs, Moira, Rakoczy, Elizabeth Piroska, Schlaich, Markus Peter, Matthews, Vance Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384225/
https://www.ncbi.nlm.nih.gov/pubmed/37520739
http://dx.doi.org/10.1016/j.isci.2023.107260