Novel mutations in U(L)24 and gH rescue efficient infection of an HSV vector retargeted to TrkA

Transductional targeting of herpes simplex virus (HSV)-based gene therapy vectors offers the potential for improved tissue-specific delivery and can be achieved by modification of the viral entry machinery to incorporate ligands that bind the desired cell surface proteins. The interaction of nerve g...

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Detalles Bibliográficos
Autores principales: Marzulli, Marco, Hall, Bonnie L., Zhang, Mingdi, Goins, William F., Cohen, Justus B., Glorioso, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384243/
https://www.ncbi.nlm.nih.gov/pubmed/37519407
http://dx.doi.org/10.1016/j.omtm.2023.06.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384243/
https://www.ncbi.nlm.nih.gov/pubmed/37519407
http://dx.doi.org/10.1016/j.omtm.2023.06.012

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