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Novel mutations in U(L)24 and gH rescue efficient infection of an HSV vector retargeted to TrkA
Transductional targeting of herpes simplex virus (HSV)-based gene therapy vectors offers the potential for improved tissue-specific delivery and can be achieved by modification of the viral entry machinery to incorporate ligands that bind the desired cell surface proteins. The interaction of nerve g...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384243/ https://www.ncbi.nlm.nih.gov/pubmed/37519407 http://dx.doi.org/10.1016/j.omtm.2023.06.012 |