Discovery of New Uracil and Thiouracil Derivatives as Potential HDAC Inhibitors

Background: Histone deacetylase inhibitors (HDACIs) are a relatively new class of potential drugs for treating cancer. Aim: Discovery of new anticancer agents targeting HDAC. Methods: New uracil and thiouracil derivatives panels were designed and synthesized as HDAC inhibitors. The synthesized compo...

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Detalles Bibliográficos
Autores principales: Elbatrawy, Omnia R., Hagras, Mohamed, El Deeb, Moshira A., Agili, Fatimah, Hegazy, Maghawry, El-Husseiny, Ahmed A., Mokhtar, Mahmoud Mohamed, Elkhawaga, Samy Y., Eissa, Ibrahim H., El-Kalyoubi, Samar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384246/
https://www.ncbi.nlm.nih.gov/pubmed/37513878
http://dx.doi.org/10.3390/ph16070966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384246/
https://www.ncbi.nlm.nih.gov/pubmed/37513878
http://dx.doi.org/10.3390/ph16070966

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