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Natural Flavonoids Quercetin and Kaempferol Targeting G2/M Cell Cycle-Related Genes and Synergize with Smac Mimetic LCL-161 to Induce Necroptosis in Cholangiocarcinoma Cells

Cholangiocarcinoma (CCA) is an aggressive cancer associated with a very poor prognosis and low survival rates, primarily due to late-stage diagnosis and low response rates to conventional chemotherapy. Therefore, there is an urgent need to identify effective therapeutic strategies that can improve p...

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Detalles Bibliográficos
Autores principales: Lomphithak, Thanpisit, Jaikla, Patthorn, Sae-Fung, Apiwit, Sonkaew, Sasiprapa, Jitkaew, Siriporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384840/
https://www.ncbi.nlm.nih.gov/pubmed/37513508
http://dx.doi.org/10.3390/nu15143090