Computer-Aided Identification of Kinase-Targeted Small Molecules for Cancer: A Review on AKT Protein

AKT (also known as PKB) is a serine/threonine kinase that plays a pivotal regulatory role in the PI3K/AKT/mTOR signaling pathway. Dysregulation of AKT activity, especially its hyperactivation, is closely associated with the development of various human cancers and resistance to chemotherapy. Over th...

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Detalles Bibliográficos
Autores principales: Primavera, Erika, Palazzotti, Deborah, Barreca, Maria Letizia, Astolfi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384952/
https://www.ncbi.nlm.nih.gov/pubmed/37513905
http://dx.doi.org/10.3390/ph16070993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384952/
https://www.ncbi.nlm.nih.gov/pubmed/37513905
http://dx.doi.org/10.3390/ph16070993

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