Pigment Epithelium-Derived Factor: Inhibition of Phosphorylation of Insulin Receptor (IR)/IR Substrate (IRS), Osteogeneration from Adipocytes, and Increased Levels Due to Doxorubicin Exposure

Objectives: Pigment epithelium-derived factor (PEDF) has been recently linked to insulin resistance and is capable of differentiating myocytes to bone. We examined in more detail the intricate signalling of the insulin pathway influenced by PEDF in skeletal myocytes. We tested whether this serpin is...

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Detalles Bibliográficos
Autores principales: Jones, Isobel C., Carnagarin, Revathy, Armstrong, Jo, Lin, Daphne P. L., Baxter-Holland, Mia, Elahy, Mina, Dass, Crispin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384968/
https://www.ncbi.nlm.nih.gov/pubmed/37514146
http://dx.doi.org/10.3390/pharmaceutics15071960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384968/
https://www.ncbi.nlm.nih.gov/pubmed/37514146
http://dx.doi.org/10.3390/pharmaceutics15071960

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