Lactate Dehydrogenase Inhibitors Suppress Borrelia burgdorferi Growth In Vitro

Borrelia burgdorferi, the causative agent of Lyme disease, has a highly reduced genome and relies heavily on glycolysis for carbon metabolism. As such, established inhibitors of lactate dehydrogenase (LDH) were evaluated in cultures to determine the extent of their impacts on B. burgdorferi growth....

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Detalles Bibliográficos
Autores principales: Lynch, Adam, Pearson, Patrick, Savinov, Sergey N., Li, Andrew Y., Rich, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384987/
https://www.ncbi.nlm.nih.gov/pubmed/37513809
http://dx.doi.org/10.3390/pathogens12070962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384987/
https://www.ncbi.nlm.nih.gov/pubmed/37513809
http://dx.doi.org/10.3390/pathogens12070962

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