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The Potential Therapeutic Application of Simvastatin for Brain Complications and Mechanisms of Action

Statins are common drugs that are clinically used to reduce elevated plasma cholesterol levels. Based on their solubility, statins are considered to be either hydrophilic or lipophilic. Amongst them, simvastatin has the highest lipophilicity to facilitate its ability to cross the blood-brain barrier...

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Detalles Bibliográficos
Autores principales: Vuu, Yen My, Kadar Shahib, Ashraf, Rastegar, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385015/
https://www.ncbi.nlm.nih.gov/pubmed/37513826
http://dx.doi.org/10.3390/ph16070914