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The Potential Therapeutic Application of Simvastatin for Brain Complications and Mechanisms of Action
Statins are common drugs that are clinically used to reduce elevated plasma cholesterol levels. Based on their solubility, statins are considered to be either hydrophilic or lipophilic. Amongst them, simvastatin has the highest lipophilicity to facilitate its ability to cross the blood-brain barrier...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385015/ https://www.ncbi.nlm.nih.gov/pubmed/37513826 http://dx.doi.org/10.3390/ph16070914 |