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Nanostructured Microparticles Repolarize Macrophages and Induce Cell Death in an In Vitro Model of Tumour-Associated Macrophages

Macrophages (MΦs) in their pro-inflammatory state (M1) suppress tumour growth, while tumour-associated MΦs (TAMs) can promote tumour progression. The aim of this study was to test the hypothesis that targeted delivery of the immune activator poly(I:C) in aspherical silica microrods (µRs) can repolar...

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Detalles Bibliográficos
Autores principales: Al-Fityan, Salma, Diesel, Britta, Fischer, Thorben, Ampofo, Emmanuel, Schomisch, Annika, Mashayekhi, Vida, Schneider, Marc, Kiemer, Alexandra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385046/
https://www.ncbi.nlm.nih.gov/pubmed/37514081
http://dx.doi.org/10.3390/pharmaceutics15071895