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Differential Genome Replication of a Unique Single-Amino-Acid Mutation in the Adenovirus-4 Component of the Live Oral Adenovirus Type 4 and Type 7 Vaccine

The FDA-approved Adenovirus Type 4 and Type 7 Vaccine, Live, Oral is highly effective and essential in preventing acute respiratory diseases (ARDs) in U.S. military recruits. Our study revealed the presence of a previously undetected mutation, not found in the wild-type human adenovirus type 4 (HAdV...

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Detalles Bibliográficos
Autores principales: Collins, Natalie D., Beaty, Shannon, Wallace, Elana, Li, Yuanzhang, Sanborn, Mark, Yang, Yu, Adhikari, Anima, Shabram, Paul, Warfield, Kelly, Karasavvas, Nicos, Kuschner, Robert A., Hang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385111/
https://www.ncbi.nlm.nih.gov/pubmed/37514960
http://dx.doi.org/10.3390/vaccines11071144