Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication

Viral replication often depends on RNA maturation and degradation processes catalyzed by viral ribonucleases, which are therefore candidate targets for antiviral drugs. Here, we synthesized and studied the antiviral properties of a novel nitrocatechol compound (1c) and other analogs that are structu...

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Detalles Bibliográficos
Autores principales: Asthana, Abhishek, Corona, Angela, Shin, Woo-Jin, Kwak, Mi-Jeong, Gaughan, Christina, Tramontano, Enzo, Jung, Jae U., Schobert, Rainer, Jha, Babal Kant, Silverman, Robert H., Biersack, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385162/
https://www.ncbi.nlm.nih.gov/pubmed/37515225
http://dx.doi.org/10.3390/v15071539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385162/
https://www.ncbi.nlm.nih.gov/pubmed/37515225
http://dx.doi.org/10.3390/v15071539

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