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Structure and Function of Hoc—A Novel Environment Sensing Device Encoded by T4 and Other Bacteriophages

Bacteriophage T4 is decorated with 155 180 Å-long fibers of the highly antigenic outer capsid protein (Hoc). In this study, we describe a near-atomic structural model of Hoc by combining cryo-electron microscopy and AlphaFold structure predictions. It consists of a conserved C-terminal capsid-bindin...

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Detalles Bibliográficos
Autores principales: Fokine, Andrei, Islam, Mohammad Zahidul, Fang, Qianglin, Chen, Zhenguo, Sun, Lei, Rao, Venigalla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385173/
https://www.ncbi.nlm.nih.gov/pubmed/37515203
http://dx.doi.org/10.3390/v15071517