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Structure and Function of Hoc—A Novel Environment Sensing Device Encoded by T4 and Other Bacteriophages
Bacteriophage T4 is decorated with 155 180 Å-long fibers of the highly antigenic outer capsid protein (Hoc). In this study, we describe a near-atomic structural model of Hoc by combining cryo-electron microscopy and AlphaFold structure predictions. It consists of a conserved C-terminal capsid-bindin...
Autores principales: | Fokine, Andrei, Islam, Mohammad Zahidul, Fang, Qianglin, Chen, Zhenguo, Sun, Lei, Rao, Venigalla B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385173/ https://www.ncbi.nlm.nih.gov/pubmed/37515203 http://dx.doi.org/10.3390/v15071517 |
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