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Radiofluorination of an Anionic, Azide-Functionalized Teroligomer by Copper-Catalyzed Azide-Alkyne Cycloaddition

This study describes the synthesis, radiofluorination and purification of an anionic amphiphilic teroligomer developed as a stabilizer for siRNA-loaded calcium phosphate nanoparticles (CaP-NPs). As the stabilizing amphiphile accumulates on nanoparticle surfaces, the fluorine-18-labeled polymer shoul...

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Detalles Bibliográficos
Autores principales: Wenzel, Barbara, Schmid, Maximilian, Teodoro, Rodrigo, Moldovan, Rareş-Petru, Lai, Thu Hang, Mitrach, Franziska, Kopka, Klaus, Fischer, Björn, Schulz-Siegmund, Michaela, Brust, Peter, Hacker, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385230/
https://www.ncbi.nlm.nih.gov/pubmed/37513105
http://dx.doi.org/10.3390/nano13142095