Modulation of Cystatin F in Human Macrophages Impacts Cathepsin-Driven Killing of Multidrug-Resistant Mycobacterium tuberculosis

Tuberculosis (TB) treatment relies primarily on 70-year-old drugs, and prophylaxis suffers from the lack of an effective vaccine. Among the 10 million people exhibiting disease symptoms yearly, 450,000 have multidrug or extensively drug-resistant (MDR or XDR) TB. A greater understanding of host and...

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Detalles Bibliográficos
Autores principales: Mandal, Manoj, Pires, David, Catalão, Maria João, Azevedo-Pereira, José Miguel, Anes, Elsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385253/
https://www.ncbi.nlm.nih.gov/pubmed/37513033
http://dx.doi.org/10.3390/microorganisms11071861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385253/
https://www.ncbi.nlm.nih.gov/pubmed/37513033
http://dx.doi.org/10.3390/microorganisms11071861

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