Coleon U, Isolated from Plectranthus mutabilis Codd., Decreases P-Glycoprotein Activity Due to Mitochondrial Inhibition

Multidrug resistance in cancer is often mediated by P-glycoprotein. Natural compounds have been suggested as a fourth generation of P-glycoprotein inhibitors. Coleon U, isolated from Plectranthus mutabilis Codd., was reported to modulate P-glycoprotein activity but the underlying mechanism has not y...

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Detalles Bibliográficos
Autores principales: Jovanović Stojanov, Sofija, Ntungwe, Epole N., Dinić, Jelena, Podolski-Renić, Ana, Pajović, Milica, Rijo, Patrícia, Pešić, Milica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385270/
https://www.ncbi.nlm.nih.gov/pubmed/37514128
http://dx.doi.org/10.3390/pharmaceutics15071942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385270/
https://www.ncbi.nlm.nih.gov/pubmed/37514128
http://dx.doi.org/10.3390/pharmaceutics15071942

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