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Coleon U, Isolated from Plectranthus mutabilis Codd., Decreases P-Glycoprotein Activity Due to Mitochondrial Inhibition
Multidrug resistance in cancer is often mediated by P-glycoprotein. Natural compounds have been suggested as a fourth generation of P-glycoprotein inhibitors. Coleon U, isolated from Plectranthus mutabilis Codd., was reported to modulate P-glycoprotein activity but the underlying mechanism has not y...
Autores principales: | Jovanović Stojanov, Sofija, Ntungwe, Epole N., Dinić, Jelena, Podolski-Renić, Ana, Pajović, Milica, Rijo, Patrícia, Pešić, Milica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385270/ https://www.ncbi.nlm.nih.gov/pubmed/37514128 http://dx.doi.org/10.3390/pharmaceutics15071942 |
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