Discovery of Novel Coumarin-Schiff Base Hybrids as Potential Acetylcholinesterase Inhibitors: Design, Synthesis, Enzyme Inhibition, and Computational Studies

To discover anti-acetylcholinesterase agents for the treatment of Alzheimer’s disease (AD), a series of novel Schiff base-coumarin hybrids was rationally designed, synthesized successfully, and structurally characterized using Fourier transform infrared (FTIR), Nuclear magnetic resonance (NMR), and...

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Detalles Bibliográficos
Autores principales: Hasan, Aso Hameed, Abdulrahman, Faruq Azeez, Obaidullah, Ahmad J., Alotaibi, Hadil Faris, Alanazi, Mohammed M., Noamaan, Mahmoud A., Murugesan, Sankaranarayanan, Amran, Syazwani Itri, Bhat, Ajmal R., Jamalis, Joazaizulfazli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385371/
https://www.ncbi.nlm.nih.gov/pubmed/37513883
http://dx.doi.org/10.3390/ph16070971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385371/
https://www.ncbi.nlm.nih.gov/pubmed/37513883
http://dx.doi.org/10.3390/ph16070971

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