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Approach to Pyrido[2,1-b][1,3]benzothiazol-1-ones via In Situ Generation of Acyl(1,3-benzothiazol-2-yl)ketenes by Thermolysis of Pyrrolo[2,1-c][1,4]benzothiazine-1,2,4-triones

Acyl(imidoyl)ketenes are highly reactive heterocumulenes that enable diversity-oriented synthesis of various drug-like heterocycles. Such ketenes, bearing heterocyclic substituents, afford angularly fused pyridin-2(1H)-ones in their [4+2]-cyclodimerization reactions. We have utilized this property f...

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Detalles Bibliográficos
Autores principales: Lystsova, Ekaterina A., Novikov, Alexander S., Dmitriev, Maksim V., Maslivets, Andrey N., Khramtsova, Ekaterina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385387/
https://www.ncbi.nlm.nih.gov/pubmed/37513367
http://dx.doi.org/10.3390/molecules28145495