Assessing Onchocerca volvulus Intensity of Infection and Genetic Diversity Using Mitochondrial Genome Sequencing of Single Microfilariae Obtained before and after Ivermectin Treatment

Onchocerciasis is a neglected tropical disease targeted for elimination using ivermectin mass administration. Ivermectin kills the microfilariae and temporarily arrests microfilariae production by the macrofilariae. We genotyped 436 microfilariae from 10 people each in Ituri, Democratic Republic of...

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Detalles Bibliográficos
Autores principales: Hedtke, Shannon M., Choi, Young-Jun, Kode, Anusha, Chalasani, Gowtam C., Sirwani, Neha, Jada, Stephen R., Hotterbeekx, An, Mandro, Michel, Siewe Fodjo, Joseph N., Amambo, Glory Ngongeh, Abong, Raphael A., Wanji, Samuel, Kuesel, Annette C., Colebunders, Robert, Mitreva, Makedonka, Grant, Warwick N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385737/
https://www.ncbi.nlm.nih.gov/pubmed/37513818
http://dx.doi.org/10.3390/pathogens12070971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385737/
https://www.ncbi.nlm.nih.gov/pubmed/37513818
http://dx.doi.org/10.3390/pathogens12070971

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