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Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates

Onchocerciasis remains a debilitating neglected tropical disease. Due to the many challenges of current control methods, an effective vaccine against the causative agent Onchocerca volvulus is urgently needed. Mice and cynomolgus macaque non-human primates (NHPs) were immunized with a vaccine consis...

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Detalles Bibliográficos
Autores principales: Ryan, Nathan M., Hess, Jessica A., Robertson, Erica J., Tricoche, Nancy, Turner, Cheri, Davis, Jenn, Petrovsky, Nikolai, Ferguson, Melissa, Rinaldi, William J., Wong, Valerie M., Shimada, Ayako, Zhan, Bin, Bottazzi, Maria Elena, Makepeace, Benjamin L., Gray, Sean A., Carter, Darrick, Lustigman, Sara, Abraham, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385774/
https://www.ncbi.nlm.nih.gov/pubmed/37515028
http://dx.doi.org/10.3390/vaccines11071212