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Synthesis of Benzocycloalkanone-Based Michael Acceptors and Biological Activities as Antimalarial and Antitrypanosomal Agents

A series of benzocycloalkanone derivatives have been prepared and evaluated as antimalarial and antitrypanosomal agents. The compounds were obtained by direct coupling of preformed 4-substituted benzaldehyde and indanone or tetralone substitutes through aldol condensation of Claisen-Schmidt using so...

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Detalles Bibliográficos
Autores principales: Mijoba, Ali, Fernandez-Moreira, Esteban, Parra-Giménez, Nereida, Espinosa-Tapia, Sandra, Blanco, Zuleyma, Ramírez, Hegira, Charris, Jaime E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385825/
https://www.ncbi.nlm.nih.gov/pubmed/37513441
http://dx.doi.org/10.3390/molecules28145569