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Synthesis and Anticancer Activity of Novel Dual Inhibitors of Human Protein Kinases CK2 and PIM-1 †

CK2 and PIM-1 are serine/threonine kinases involved in the regulation of many essential processes, such as proliferation, differentiation, and apoptosis. Inhibition of CK2 and PIM-1 kinase activity has been shown to significantly reduce the viability of cancer cells by inducing apoptosis. A series o...

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Detalles Bibliográficos
Autores principales: Wińska, Patrycja, Wielechowska, Monika, Koronkiewicz, Mirosława, Borowiecki, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385865/
https://www.ncbi.nlm.nih.gov/pubmed/37514177
http://dx.doi.org/10.3390/pharmaceutics15071991