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Sertaconazole-repurposed nanoplatform enhances lung cancer therapy via CD44-targeted drug delivery

BACKGROUND: Lung cancer is one of the most frequent causes of cancer-related deaths worldwide. Drug repurposing and nano-drug delivery systems are attracting considerable attention for improving anti-cancer therapy. Sertaconazole (STZ), an antifungal agent, has been reported to exhibit cytotoxicity...

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Detalles Bibliográficos
Autores principales: Liu, Ruolan, Li, Qiong, Qin, Siyuan, Qiao, Ling, Yang, Mei, Liu, Shanshan, Nice, Edouard C., Zhang, Wei, Huang, Canhua, Zheng, Shaojiang, Gao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385912/
https://www.ncbi.nlm.nih.gov/pubmed/37507782
http://dx.doi.org/10.1186/s13046-023-02766-2