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Targeted ablation of signal transducer and activator of transduction 1 alleviates inflammation by microglia/macrophages and promotes long-term recovery after ischemic stroke

BACKGROUND: Brain microglia and macrophages (Mi/MΦ) can shift to a harmful or advantageous phenotype following an ischemic stroke. Identification of key molecules that regulate the transformation of resting Mi/MΦ could aid in the development of innovative therapies for ischemic stroke. The transcrip...

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Detalles Bibliográficos
Autores principales: Han, Wenxuan, Pu, Hongjian, Li, Sicheng, Liu, Yaan, Zhao, Yongfang, Xu, Mingyue, Chen, Caixia, Wu, Yun, Yang, Tuo, Ye, Qing, Wang, Hong, Stetler, R. Anne, Chen, Jun, Shi, Yejie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385956/
https://www.ncbi.nlm.nih.gov/pubmed/37516843
http://dx.doi.org/10.1186/s12974-023-02860-4