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On the Road towards Small-Molecule Programmed Cell Death 1 Ligand 1 Positron Emission Tomography Tracers: A Ligand-Based Drug Design Approach

PD-1/PD-L1 immune checkpoint blockade for cancer therapy showed promising results in clinical studies. Further endeavors are required to enhance patient stratification, as, at present, only a small portion of patients with PD-L1-positive tumors (as determined by PD-L1 targeted immunohistochemistry;...

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Detalles Bibliográficos
Autores principales: Bamminger, Karsten, Pichler, Verena, Vraka, Chrysoula, Nehring, Tina, Pallitsch, Katharina, Lieder, Barbara, Hacker, Marcus, Wadsak, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10385977/
https://www.ncbi.nlm.nih.gov/pubmed/37513962
http://dx.doi.org/10.3390/ph16071051