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A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer
BACKGROUND: Prostate cancer is a major cause of cancer morbidity and mortality in men worldwide. Androgen deprivation therapy (ADT) has proven effective in early-stage androgen-sensitive disease, but prostate cancer gradually develops into an androgen-resistant metastatic state in the vast majority...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386253/ https://www.ncbi.nlm.nih.gov/pubmed/37507762 http://dx.doi.org/10.1186/s13046-023-02769-z |