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Coptisine Inhibits Influenza Virus Replication by Upregulating p21

The activation of innate antiviral immunity is a promising approach for combatting viral infections. In this study, we screened Chinese herbs that activated human immunity and identified coptisine as a potent inhibitor of the influenza virus with an EC(50) of 10.7 μM in MDCK cells. The time of an ad...

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Detalles Bibliográficos
Autores principales: He, Ming-Feng, Liang, Jian-Hui, Shen, Yan-Ni, Zhang, Chao-Wei, Yang, Kuang-Yang, Liu, Li-Chu, Xie, Qian, Hu, Chun, Song, Xun, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386263/
https://www.ncbi.nlm.nih.gov/pubmed/37513270
http://dx.doi.org/10.3390/molecules28145398