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Metformin attenuates chronic lung allograft dysfunction: evidence in rat models

BACKGROUND: Chronic lung allograft dysfunction (CLAD) directly causes an abysmal long-term prognosis after lung transplantation (LTx), but effective and safe drugs are not available. Metformin exhibits high therapeutic potential due to its antifibrotic and immunomodulatory effects; however, it is un...

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Detalles Bibliográficos
Autores principales: Tian, Dong, Zheng, Xiangyun, Tang, Hongtao, Huang, Heng, Wang, Junjie, Xu, Lin, Li, Caihan, Yan, Haoji, Yu, Ruixuan, Nan, Jinzhu, Liu, Menggen, Guo, Xiaoguang, Jian, Shunhai, Wang, Tao, Deng, Senyi, Pu, Qiang, Liu, Lunxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386298/
https://www.ncbi.nlm.nih.gov/pubmed/37516880
http://dx.doi.org/10.1186/s12931-023-02492-5