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Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ) Loaded with Platinum-Based Anticancer Agents—A Novel Polymer Formulation for Anticancer Therapy

Quaternary ammonium palmitoyl glycol chitosan (GCPQ) has already shown beneficial drug delivery properties and has been studied as a carrier for anticancer agents. Consequently, we synthesised cytotoxic platinum(IV) conjugates of cisplatin, carboplatin and oxaliplatin by coupling via amide bonds to...

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Detalles Bibliográficos
Autores principales: Lerchbammer-Kreith, Yvonne, Hejl, Michaela, Sommerfeld, Nadine S., Weng-Jiang, Xian, Odunze, Uchechukwu, Mellor, Ryan D., Workman, David G., Jakupec, Michael A., Schätzlein, Andreas G., Uchegbu, Ijeoma F., Galanski, Mathea S., Keppler, Bernhard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386324/
https://www.ncbi.nlm.nih.gov/pubmed/37513938
http://dx.doi.org/10.3390/ph16071027