Indole-Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents—Synthesis, In Vitro and In Silico Studies

A series of 2-(1H-indol-2-yl)-3-acrylonitrile derivatives, 2a–x, 3, 4a–b, 5a–d, 6a–b, and 7, were synthesized as potential antitumor and antimicrobial agents. The structures of the prepared compounds were evaluated based on elemental analysis, IR, (1)H- and (13)NMR, as well as MS spectra. X-ray crys...

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Detalles Bibliográficos
Autores principales: Kornicka, Anita, Gzella, Karol, Garbacz, Katarzyna, Jarosiewicz, Małgorzata, Gdaniec, Maria, Fedorowicz, Joanna, Balewski, Łukasz, Kokoszka, Jakub, Ordyszewska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386429/
https://www.ncbi.nlm.nih.gov/pubmed/37513830
http://dx.doi.org/10.3390/ph16070918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386429/
https://www.ncbi.nlm.nih.gov/pubmed/37513830
http://dx.doi.org/10.3390/ph16070918

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