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Indole-Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents—Synthesis, In Vitro and In Silico Studies
A series of 2-(1H-indol-2-yl)-3-acrylonitrile derivatives, 2a–x, 3, 4a–b, 5a–d, 6a–b, and 7, were synthesized as potential antitumor and antimicrobial agents. The structures of the prepared compounds were evaluated based on elemental analysis, IR, (1)H- and (13)NMR, as well as MS spectra. X-ray crys...
Autores principales: | Kornicka, Anita, Gzella, Karol, Garbacz, Katarzyna, Jarosiewicz, Małgorzata, Gdaniec, Maria, Fedorowicz, Joanna, Balewski, Łukasz, Kokoszka, Jakub, Ordyszewska, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386429/ https://www.ncbi.nlm.nih.gov/pubmed/37513830 http://dx.doi.org/10.3390/ph16070918 |
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