Stimulation of Autophagy by Dapagliflozin Mitigates Cadmium-Induced Testicular Dysfunction in Rats: The Role of AMPK/mTOR and SIRT1/Nrf2/HO-1 Pathways

Cadmium (Cd) is a widespread environmental pollutant that triggers testicular dysfunction. Dapagliflozin is a selective sodium-glucose co-transporter-2 inhibitor with notable antioxidant and anti-apoptotic features. It has shown marked cardio-, reno-, hepato-, and neuroprotective effects. Yet, its e...

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Detalles Bibliográficos
Autores principales: Arab, Hany H., Fikry, Ebtehal Mohammad, Alsufyani, Shuruq E., Ashour, Ahmed M., El-Sheikh, Azza A. K., Darwish, Hany W., Al-Hossaini, Abdullah M., Saad, Muhammed A., Al-Shorbagy, Muhammad Y., Eid, Ahmed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386496/
https://www.ncbi.nlm.nih.gov/pubmed/37513918
http://dx.doi.org/10.3390/ph16071006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386496/
https://www.ncbi.nlm.nih.gov/pubmed/37513918
http://dx.doi.org/10.3390/ph16071006

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