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Gypenosides Synergistically Reduce the Extracellular Matrix of Hepatic Stellate Cells and Ameliorate Hepatic Fibrosis in Mice

Liver fibrosis resulting from chronic liver damage is becoming one of the major threats to health worldwide. Active saponin constituents isolated from Gynostemma pentaphyllum were found to possess a protective effect in liver diseases. Here, we obtained a naturally abundant gypenoside, XLVI, and eva...

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Detalles Bibliográficos
Autores principales: Li, Han, Wang, Hanghang, Yang, Aiping, Xue, Mingzhen, Wang, Junyang, Lv, Qi, Liu, Jian, Hu, Lihong, Zhang, Yinan, Wang, Xiachang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386501/
https://www.ncbi.nlm.nih.gov/pubmed/37513321
http://dx.doi.org/10.3390/molecules28145448