Differential responses of pulmonary vascular cells from PAH patients and controls to TNFα and the effect of the BET inhibitor JQ1

BACKGROUND: Pulmonary arterial hypertension (PAH) encompasses a group of diseases characterized by raised pulmonary vascular resistance, resulting from vascular remodelling and inflammation. Bromodomain and extra-terminal (BET) proteins are required for the expression of a subset of NF-κB-induced in...

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Detalles Bibliográficos
Autores principales: Mumby, Sharon, Perros, Frederic, Grynblat, Julien, Manaud, Gregoire, Papi, Alberto, Casolari, Paolo, Caramori, Gaetano, Humbert, Marc, John Wort, S., Adcock, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386603/
https://www.ncbi.nlm.nih.gov/pubmed/37516840
http://dx.doi.org/10.1186/s12931-023-02499-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386603/
https://www.ncbi.nlm.nih.gov/pubmed/37516840
http://dx.doi.org/10.1186/s12931-023-02499-y

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