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Establishment and Evaluation of a Parametric Population Pharmacokinetic Model Repository for Ganciclovir and Valganciclovir

Background: Ganciclovir and valganciclovir are used for prophylaxis and treatment of cytomegalovirus infection. However, there is great interindividual variability in ganciclovir’s pharmacokinetics (PK), highlighting the importance of individualized dosing. To facilitate model-informed precision dos...

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Detalles Bibliográficos
Autores principales: Yang, Wenyu, Mak, Wenyao, Gwee, Amanda, Gu, Meng, Wu, Yue, Shi, Yufei, He, Qingfeng, Xiang, Xiaoqiang, Han, Bing, Zhu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386724/
https://www.ncbi.nlm.nih.gov/pubmed/37513988
http://dx.doi.org/10.3390/pharmaceutics15071801