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Establishment and Evaluation of a Parametric Population Pharmacokinetic Model Repository for Ganciclovir and Valganciclovir
Background: Ganciclovir and valganciclovir are used for prophylaxis and treatment of cytomegalovirus infection. However, there is great interindividual variability in ganciclovir’s pharmacokinetics (PK), highlighting the importance of individualized dosing. To facilitate model-informed precision dos...
Autores principales: | Yang, Wenyu, Mak, Wenyao, Gwee, Amanda, Gu, Meng, Wu, Yue, Shi, Yufei, He, Qingfeng, Xiang, Xiaoqiang, Han, Bing, Zhu, Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386724/ https://www.ncbi.nlm.nih.gov/pubmed/37513988 http://dx.doi.org/10.3390/pharmaceutics15071801 |
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