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Dengue Virus Infection Alters Inter-Endothelial Junctions and Promotes Endothelial–Mesenchymal-Transition-like Changes in Human Microvascular Endothelial Cells

Dengue virus (DENV) is a pathogenic arbovirus that causes human disease. The most severe stage of the disease (severe dengue) is characterized by vascular leakage, hypovolemic shock, and organ failure. Endothelial dysfunction underlies these phenomena, but the causal mechanisms of endothelial dysfun...

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Detalles Bibliográficos
Autores principales: Escudero-Flórez, Manuela, Torres-Hoyos, David, Miranda-Brand, Yaneth, Boudreau, Ryan L., Gallego-Gómez, Juan Carlos, Vicente-Manzanares, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386726/
https://www.ncbi.nlm.nih.gov/pubmed/37515125
http://dx.doi.org/10.3390/v15071437