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Dapagliflozin-affected endothelial dysfunction and altered gut microbiota in mice with heart failure

AIM: To investigate the potential microbiome profile of a mouse model with heart failure (HF) during dapagliflozin treatment. METHOD: An HF model was constructed in 8-week-old male mice, and cardiac tissues were analyzed using histological staining. Hemodynamic indexes were measured, and fecal sampl...

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Detalles Bibliográficos
Autores principales: Bao, Nandi, Liu, Xiaoli, Zhong, Xiaoling, Jia, Shuangshuang, Hua, Ning, Zhang, Li, Mo, Guoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386824/
https://www.ncbi.nlm.nih.gov/pubmed/37520255
http://dx.doi.org/10.7717/peerj.15589