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Nanodepots Encapsulating a Latency Reversing Agent and Broadly Neutralizing Antibody Enhance Natural Killer Cell Cytotoxicity Against an in vitro Model of Latent HIV

PURPOSE: Current antiretroviral therapies (ART) for human immunodeficiency virus (HIV) are not curative, as the virus persists in latent reservoirs, requiring lifelong adherence to ART and increasing the risk of co-morbidities. “Shock and kill” approaches to reactivate HIV from latent reservoirs fol...

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Detalles Bibliográficos
Autores principales: Ghofrani, Joshua, Bowen, Allan, Chen, Jie, Balakrishnan, Preethi Bala, Powell, Allison B, Cherukula, Kondareddy, Cruz, Conrad Russell Y, Jones, R Brad, Lynch, Rebecca M, Sweeney, Elizabeth E, Fernandes, Rohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10386837/
https://www.ncbi.nlm.nih.gov/pubmed/37520301
http://dx.doi.org/10.2147/IJN.S401304